Industry — Industrial Biotechnology

Enzyme engineering, biocatalysis and green-chemistry substitution

Directed evolution and display selection applied to your substrate and your process conditions, protein purification workflow design, and condition optimisation for enzymes that sit on a production critical path.

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8 of the 21 portfolio entries are tagged for this sector. Every price shown is indicative; final terms are negotiated per scope.

Portfolio entries for this sector

Enzyme engineering · Directed evolution

Haloalkane Dehalogenase Engineering Platform

Carbon–halogen bond cleavage for remediation and industrial process chemistry. Directed evolution, ribosome display and catalytic optimisation applied to your substrate — relevant wherever a process generates or handles halogenated streams.

Evidence: Capability & method data under NDA
Stage: Pilot-ready · licensing open
Indicative: € 15 000 – 120 000negotiable by scope and application

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Protein biophysics · Formulation support

Protein Stability & Formulation Platform

Know before you formulate. DSC, fluorescence probes and dynamic light scattering map thermodynamic and kinetic stability; buffer, salt and pH screening and aggregation risk profiling are run on your protein rather than on a generic prediction.

Evidence: Method portfolio · report under NDA
Stage: Pilot-ready
Indicative: € 8 000 – 50 000negotiable by scope and application

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Protease activity · Condition optimisation

HRV 3C Protease Optimisation Platform

Kosmotropic anions increase HRV 3C protease rigidity, stability and catalytic efficiency — a published finding with direct workflow consequences. If your production depends on a cleavage step, this tells you which conditions maximise yield and enzyme lifetime.

Evidence: Peer-reviewed 2022 (Biophys. Chem.)
Stage: Pilot-ready
Indicative: € 6 000 – 35 000negotiable by scope and application

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Recombinant protein purification

MBP Fusion Protein Purification Platform

One-step affinity purification and immobilisation for MBP-tagged proteins. The MBP tag substantially improves solubility for difficult-to-express fusion partners — a cost-effective alternative for teams spending too much on multi-step chromatography of insoluble targets.

Evidence: Method portfolio · report under NDA
Stage: Pilot-ready
Indicative: € 5 000 – 40 000negotiable by scope and application

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Aggregation · Self-assembly

Amyloid & Protein Aggregation Platform

Aggregation quietly kills promising protein therapeutics and formulations. The platform screens stress conditions, maps aggregation kinetics and identifies stabilisation strategies. It also covers spider-silk self-assembly systems for biomedical and biomaterial applications.

Evidence: Method portfolio · report under NDA
Stage: Pilot-ready · licensing open
Indicative: € 8 000 – 60 000negotiable by scope and application

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C1Fluorescent probe

APF · C₂₆H₁₇NO₅ · MW 433.42 g/mol

Aminophenyl Fluorescein (APF)

Cell-permeable, photostable probe for selective detection of highly reactive oxygen and nitrogen species. On reaction with hROS/hRNS it is cleaved to release free fluorescein, giving a strong signal on standard microscopes, flow cytometers and plate readers.

Selectivity: OCl⁻ · HO· · ONOO⁻
Stage: Synthesis to order
Indicative: Price on requestby quantity and application

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NPF · C₂₆H₁₅NO₇ · MW 463.40 g/mol

Nitrophenyl Fluorescein (NPF)

A substrate and reporter group for enzymatic and bioanalytical assays. Enzyme-mediated hydrolysis or reduction of the nitrophenyl ester bond changes absorbance and fluorescence, producing an optical signal proportional to enzyme activity or analyte concentration.

Readout: Absorbance · fluorescence
Stage: Synthesis to order
Indicative: Price on requestby quantity and application

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C7Bioconjugation tools

Saccharide derivatives · Reactive intermediates

Sugar Isothiocyanates & Aminosugars

Sugar isothiocyanates form covalent bonds with amines, which makes them useful for conjugating sugars to proteins or fluorescent labels and tracking sugar transport in vivo. Aminosugars are building blocks for glycoprotein and glycolipid synthesis, joint-nutrition compounds and antibiotic development targeting bacterial cell walls.

Evidence: Synthetic capability · characterisation on request
Stage: Synthesis to order · licensing open
Indicative: Price on requestcustom quantities available

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How an engagement typically starts here

Model 01 · Start here

Discovery call

A focused 30-minute conversation about your pipeline, the compound or protein of interest, the application and IP considerations. No commitment. We establish together whether there is a fit and what the right next step is.

Deliverable: Verbal assessment · recommended next step
Duration: 30 minutes
Price: Freepaid expert consultation available in selected cases

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Model 02

Feasibility scan

Before lab time is allocated, we assess your target, application and intended use scientifically and technically. The fastest way to test assumptions — and far cheaper than a pilot that runs in the wrong direction.

Deliverable: Written feasibility assessment
Duration: By scope
Price: € 1 500 – 5 000or negotiated

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Model 04

Custom research pilot

An 8–12 week R&D engagement with defined milestones, mechanistic data and a full deliverable package including a technical report and recommendations. For companies that need a complete scientific narrative, not just a screen result.

Deliverable: Mechanistic dataset · report · recommendations
Duration: 8–12 weeks
Price: € 10 000 – 40 000or negotiated

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Common questions

How does an engagement start?

With a free 30-minute discovery call. We establish whether there is a fit and what the right next step is. Nothing is committed at that point.

Can we sign an NDA before we describe our project?

Yes. Tick the NDA box on the inquiry form and we arrange it before any disclosure.

Are the prices on this site binding?

No. They are indicative ranges so that you can size a project before contacting us. Final terms are negotiated per scope.

How quickly do you reply?

Every inquiry is acknowledged within one working day and answered by the responsible group leader within three.

What happens if you cannot help?

We say so, early, and where we can we point you to someone who can. A negative feasibility answer delivered quickly is a useful result.

Tell us what you are trying to achieve.

A free 30-minute call establishes whether there is a fit and what the right next step is. Every inquiry is acknowledged within one working day and answered by the responsible group leader within three.

Book a 30-minute discovery call Send an inquiry instead