C7 Organic Synthesis · Reactive intermediates · glycoprotein and glycolipid building blocks

Sugar Isothiocyanates & Aminosugars

Sugar isothiocyanates form covalent bonds with amines, which makes them useful for conjugating sugars to proteins or fluorescent labels and tracking sugar transport in vivo. Aminosugars are building blocks for glycoprotein and glycolipid synthesis, joint-nutrition compounds and antibiotic development targeting bacterial cell walls.

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Evidence: Synthetic capability · characterisation on request
Stage: Synthesis to order · licensing open
Indicative: Price on requestcustom quantities available

Structure of a sugar isothiocyanate — protected furanose intermediate — Sugar isothiocyanate — protected furanose

Structure of an aminosugar — protected furanose bearing an NH2 group — Aminosugar — protected furanose with –NH₂

Scientific summary

Sugar isothiocyanates are highly reactive intermediates that form covalent bonds with amines. That makes them useful for conjugating sugars to proteins or fluorescent labels, which in turn enables tracking of sugar transport in vivo. Aminosugars — in which a hydroxyl is replaced by –NH₂ — are key building blocks in glycoprotein and glycolipid synthesis, with applications in joint-nutrition compounds and in antibiotic development targeting bacterial cell walls.

Applications

Bioconjugation of sugars to proteins and labels
Glycoprotein and glycolipid synthesis
In vivo sugar transport tracking
Chondroprotective compound development
Antibiotic development targeting cell wall biosynthesis

Specification

Compound type	Protected furanose isothiocyanates and aminosugars
Research group	Department of Organic Chemistry, Faculty of Science, UPJŠ
Evidence status	Synthesis capability; characterisation data on request
Supply	Synthesised to order · custom quantities available
Engagement	Custom synthesis · pilot · licensing
Indicative price	Price on request, by scope and application

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