C1Fluorescent probe
APF · C26H17NO5 · MW 433.42 g/mol
Cell-permeable, photostable probe for selective detection of highly reactive oxygen and
nitrogen species. On reaction with hROS/hRNS it is cleaved to release free fluorescein, giving a
strong signal on standard microscopes, flow cytometers and plate readers.
- hROS / hRNS detection
- Live-cell imaging
- Flow cytometry
- HCS antioxidant screening
- Selectivity
- OCl⁻ · HO· · ONOO⁻
- Stage
- Synthesis to order
- Indicative
- Price on requestby quantity and application
C2
NPF · C26H15NO7 · MW 463.40 g/mol
A substrate and reporter group for enzymatic and bioanalytical assays. Enzyme-mediated
hydrolysis or reduction of the nitrophenyl ester bond changes absorbance and fluorescence,
producing an optical signal proportional to enzyme activity or analyte concentration.
- Enzyme activity reporter
- Esterase substrates
- Hydrolase profiling
- Plate-reader compatible
- Readout
- Absorbance · fluorescence
- Stage
- Synthesis to order
- Indicative
- Price on requestby quantity and application
C3
Pyrrolidine-based sphingolipid analogues
Synthetic compounds designed to mimic the structure and function of natural sphingolipids. The
five-membered nitrogen heterocycle improves chemical stability and affinity for specific enzymes,
making these candidates for inhibitor development and lysosomal disorder research.
- Glucosylceramide synthase inhibitors
- Gaucher disease research
- Ceramide regulation
- Anticancer screening
- Evidence
- Synthetic capability · characterisation on request
- Stage
- Synthesis to order · licensing open
- Indicative
- Price on requestby quantity and application
C4
Sphingoid bases · D/L-ribo & D/L-arabino
Natural components of plants, yeasts and human skin. Four stereoisomers differ in the spatial
arrangement of hydroxyl groups, which makes the set useful for enzyme stereoselectivity studies.
D-ribo-phytosphingosine is the most common natural form.
- Cosmetics & dermatology
- Skin barrier
- Anti-acne research
- Enzyme stereoselectivity
- Evidence
- Synthetic capability · characterisation on request
- Stage
- Synthesis to order · licensing open
- Indicative
- Price on requestby quantity and application
C5
Amino derivatives · D-/L-erythro · –NH₂ at C3
Dihydrosphingosine derivatives in which the C3 hydroxyl is replaced by an amino group. The
D-erythro and L-erythro isomers show distinct biological activity, and the amino group enables
stronger protein kinase C inhibition — relevant to cell signalling and apoptosis research.
- Molecular probes
- PKC inhibition
- Apoptosis research
- Sphingolipid metabolism
- Evidence
- Synthetic capability · characterisation on request
- Stage
- Synthesis to order
- Indicative
- Price on requestby quantity and application
C6
Sphingosine analogues · S1P pathway
Sphingosine is the fundamental building block of sphingolipids. These analogues carry modified
chain lengths or functional groups for precise modulation of sphingosine-1-phosphate signalling —
a pathway studied in autoimmune disease and tumour angiogenesis research.
- S1P pathway modulation
- Multiple sclerosis research
- Angiogenesis research
- Biomedical research
- Evidence
- Synthetic capability · characterisation on request
- Stage
- Synthesis to order · licensing open
- Indicative
- Price on requestby quantity and application
C7Bioconjugation tools
Saccharide derivatives · Reactive intermediates
Sugar isothiocyanates form covalent bonds with amines, which makes them useful for conjugating
sugars to proteins or fluorescent labels and tracking sugar transport in vivo. Aminosugars are
building blocks for glycoprotein and glycolipid synthesis, joint-nutrition compounds and
antibiotic development targeting bacterial cell walls.
- Bioconjugation
- Glycoprotein synthesis
- Glycolipid building blocks
- Antibiotic development
- Chondroprotectives
- Evidence
- Synthetic capability · characterisation on request
- Stage
- Synthesis to order · licensing open
- Indicative
- Price on requestcustom quantities available
