C6 Organic Synthesis · S1P pathway modulators · modified chain and functional groups

D-erythro-Sphingosine Analogues

Sphingosine is the fundamental building block of sphingolipids. These analogues carry modified chain lengths or functional groups for precise modulation of sphingosine-1-phosphate signalling — a pathway studied in autoimmune disease and tumour angiogenesis research.

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Evidence: Synthetic capability · characterisation on request
Stage: Synthesis to order · licensing open
Indicative: Price on requestby quantity and application

Structures of D-erythro-sphingosine analogues — D-erythro-sphingosine analogues

Scientific summary

Sphingosine is the fundamental building block of sphingolipids. These analogues carry modified chain lengths or functional groups intended for precise modulation of sphingosine-1-phosphate (S1P) signalling — a pathway studied in autoimmune disease research, including multiple sclerosis models, and in tumour angiogenesis.

How they are used

As a defined series rather than single compounds: varying one structural feature at a time across the set is what makes a structure–activity relationship visible in an S1P assay.

Applications

S1P pathway modulation studies
Multiple sclerosis research models
Angiogenesis research
Biomedical research tool compounds

Specification

Compound type	Sphingosine analogues (D-erythro series)
Research group	Department of Organic Chemistry, Faculty of Science, UPJŠ
Evidence status	Synthesis capability; characterisation data on request
Supply	Synthesised to order · analogue series possible
Engagement	Custom synthesis · pilot · licensing
Indicative price	Price on request, by quantity and application

Disease areas describe the research context. These are research tool compounds; no therapeutic, clinical or regulatory status is claimed.

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