C4 Organic Synthesis · Sphingoid bases · D/L-ribo and D/L-arabino stereoisomers

Phytosphingosines & Analogues

Natural components of plants, yeasts and human skin. Four stereoisomers differ in the spatial arrangement of hydroxyl groups, which makes the set useful for enzyme stereoselectivity studies. D-ribo-phytosphingosine is the most common natural form.

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Evidence: Synthetic capability · characterisation on request
Stage: Synthesis to order · licensing open
Indicative: Price on requestby quantity and application

Structures of D-ribo-phytosphingosine and its stereochemical analogues — D-ribo-phytosphingosine and stereochemical analogues

Scientific summary

Phytosphingosines are natural components of plants, yeasts and human skin. We supply four stereoisomers — D/L-ribo and D/L-arabino — which differ in the spatial arrangement of their hydroxyl groups. D-ribo-phytosphingosine is the most common natural form.

Why the full stereoisomer set is useful

Having all four isomers from one synthetic route, characterised the same way, makes enzyme stereoselectivity measurable rather than inferred. For cosmetic and dermatological work it also lets you test whether activity tracks the natural configuration or not.

Applications

Cosmetics and dermatology research
Skin barrier protection studies
Anti-acne research (Cutibacterium acnes models)
Enzyme stereoselectivity studies

Specification

Compound type	Sphingoid bases, four stereoisomers
Stereochemistry	D-ribo · L-ribo · D-arabino · L-arabino
Research group	Department of Organic Chemistry, Faculty of Science, UPJŠ
Evidence status	Synthesis capability; characterisation data on request
Supply	Synthesised to order · single isomers or full set
Engagement	Custom synthesis · pilot · licensing
Indicative price	Price on request, by quantity and application

Cosmetic ingredient status, safety assessment and marketing claims are regulated separately in each market and remain the responsibility of the partner placing the product on the market.

What happens next

Book a call or send an inquiry. Tell us the target, the application and the timeline.
We answer within three working days — including when the answer is that we cannot help.
NDA before disclosure, if you need one. Tick the box on the form.
Feasibility scan or pilot proposal with a defined scope, deliverable and price.

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Common questions

How does an engagement start?

With a free 30-minute discovery call. We establish whether there is a fit and what the right next step is. Nothing is committed at that point.

Can we sign an NDA before we describe our project?

Yes. Tick the NDA box on the inquiry form and we arrange it before any disclosure.

Are the prices on this site binding?

No. They are indicative ranges so that you can size a project before contacting us. Final terms are negotiated per scope.

How quickly do you reply?

Every inquiry is acknowledged within one working day and answered by the responsible group leader within three.

What happens if you cannot help?

We say so, early, and where we can we point you to someone who can. A negative feasibility answer delivered quickly is a useful result.

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Tell us what you are trying to achieve.

A free 30-minute call establishes whether there is a fit and what the right next step is. Every inquiry is acknowledged within one working day and answered by the responsible group leader within three.

Book a 30-minute discovery call Send an inquiry instead