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B7 Proteins & Enzymes · Aggregation · Self-assembly

Amyloid & Protein Aggregation Platform

Aggregation quietly kills promising protein therapeutics and formulations. The platform screens stress conditions, maps aggregation kinetics and identifies stabilisation strategies. It also covers spider-silk self-assembly systems for biomedical and biomaterial applications.

Evidence
Method portfolio · report under NDA
Stage
Pilot-ready · licensing open
Indicative
€ 8 000 – 60 000negotiable by scope and application

What the platform does

Aggregation is usually detected late and diagnosed poorly. The platform screens stress conditions systematically, follows aggregation kinetics rather than only endpoints, and identifies which stabilisation strategies actually shift the curve for your protein. It also covers engineered self-assembly — including spider-silk systems — where controlled assembly is the goal rather than the failure mode.

Two very different use cases

Preventing aggregation in a therapeutic or industrial protein, and exploiting assembly to build a biomaterial, use the same measurements pointed in opposite directions. Both are supported.

Applications

  • Therapeutic protein aggregation risk
  • Formulation stress screening
  • Neurodegeneration-related aggregation research
  • Self-assembling biomaterials

Assays & readouts available

  • Aggregation kinetics
  • Stress condition matrices (temperature, pH, ionic strength)
  • Light scattering and fluorescence probes
  • Stabilisation strategy ranking

Specification

Technology typeAggregation and self-assembly characterisation
Research groupCIB — Centre for Interdisciplinary Biosciences
Evidence statusPilot-ready capability; results generated for the partner under NDA
Typical pilotBioactivity/biophysics pilot, 4–8 weeks, or longer programme
DeliverablesKinetic data, condition ranking, stabilisation recommendations
EngagementFeasibility scan · pilot · licensing · co-development
Indicative price€ 8 000 – 60 000, negotiable by scope and application

Aggregation research relevant to neurodegeneration is basic science. Nothing in this platform constitutes a diagnostic, therapeutic or clinical claim.

What happens next

  1. Book a call or send an inquiry. Tell us the target, the application and the timeline.
  2. We answer within three working days — including when the answer is that we cannot help.
  3. NDA before disclosure, if you need one. Tick the box on the form.
  4. Feasibility scan or pilot proposal with a defined scope, deliverable and price.

Book a 30-minute discovery call Send an inquiry

Common questions

How does an engagement start?
With a free 30-minute discovery call. We establish whether there is a fit and what the right next step is. Nothing is committed at that point.
Can we sign an NDA before we describe our project?
Yes. Tick the NDA box on the inquiry form and we arrange it before any disclosure.
Are the prices on this site binding?
No. They are indicative ranges so that you can size a project before contacting us. Final terms are negotiated per scope.
How quickly do you reply?
Every inquiry is acknowledged within one working day and answered by the responsible group leader within three.
What happens if you cannot help?
We say so, early, and where we can we point you to someone who can. A negative feasibility answer delivered quickly is a useful result.

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Tell us what you are trying to achieve.

A free 30-minute call establishes whether there is a fit and what the right next step is. Every inquiry is acknowledged within one working day and answered by the responsible group leader within three.