B6 Proteins & Enzymes · Membrane protein · GPCR

Membrane Protein & GPCR Feasibility Platform

High-risk, high-reward targets made more tractable: candidate selection, expression and purification strategy, hot-spot identification, and yeast or ribosome display for solubility improvement. Feasibility first — before you commit a full GPCR budget.

Book a 30-minute discovery call Request the data package

Evidence: Feasibility assessment · under NDA
Stage: Feasibility → pilot · licensing open
Indicative: € 15 000 – 120 000negotiable by scope and application

What the platform does

Membrane proteins and GPCRs are the highest-value and highest-failure targets in the portfolio. The platform is deliberately structured as feasibility first: candidate selection, an expression and purification strategy, hot-spot identification, and display-based approaches (yeast, ribosome) to improve solubility — before a full programme budget is committed.

The honest framing

We do not promise that any given GPCR will become tractable. We do promise to tell you early, on evidence, whether it is worth continuing — which is the more valuable answer when it is negative.

Applications

GPCR candidate triage
Expression and purification strategy
Hot-spot identification
Solubility improvement by display methods

Methods available

Target tractability assessment
Yeast display
Ribosome display
Construct and detergent/condition screening

Specification

Technology type	Membrane protein feasibility and engineering
Research group	CIB — Centre for Interdisciplinary Biosciences
Evidence status	Feasibility assessment produced per target, under NDA
Typical pilot	Feasibility scan, then a multi-month programme if positive
Deliverables	Feasibility report, recommended strategy, go/no-go rationale
Engagement	Feasibility scan · programme · licensing · co-development
Indicative price	€ 15 000 – 120 000, negotiable by scope and application

What happens next

Book a call or send an inquiry. Tell us the target, the application and the timeline.
We answer within three working days — including when the answer is that we cannot help.
NDA before disclosure, if you need one. Tick the box on the form.
Feasibility scan or pilot proposal with a defined scope, deliverable and price.

Book a 30-minute discovery call Send an inquiry

Common questions

How does an engagement start?

With a free 30-minute discovery call. We establish whether there is a fit and what the right next step is. Nothing is committed at that point.

Can we sign an NDA before we describe our project?

Yes. Tick the NDA box on the inquiry form and we arrange it before any disclosure.

Are the prices on this site binding?

No. They are indicative ranges so that you can size a project before contacting us. Final terms are negotiated per scope.

How quickly do you reply?

Every inquiry is acknowledged within one working day and answered by the responsible group leader within three.

What happens if you cannot help?

We say so, early, and where we can we point you to someone who can. A negative feasibility answer delivered quickly is a useful result.

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Tell us what you are trying to achieve.

A free 30-minute call establishes whether there is a fit and what the right next step is. Every inquiry is acknowledged within one working day and answered by the responsible group leader within three.

Book a 30-minute discovery call Send an inquiry instead